I have one of those in my SNES console (granted, taken apart and directly connected to the SNES ports, but same principal). They work great! I do notice a ever-so-slight delay (maybe 5~10ms) in reaction time on this however. I’m trying to run my SNES controllers via the GPIO (to no avail yet) to see if that’s any better. When I control a game with my keyboard there is 0 delay.
But all in all, yes it works. Plug and play (no config or drivers needed), and it recognizes both controllers separately.